Mast cell ciwon sukari a cikin cats - Alamun, magani da tsinkaya

Mawallafi: Peter Berry
Ranar Halitta: 18 Yuli 2021
Sabuntawa: 14 Nuwamba 2024
Anonim
Mast cell ciwon sukari a cikin cats - Alamun, magani da tsinkaya - Dabbobin Dabbobi
Mast cell ciwon sukari a cikin cats - Alamun, magani da tsinkaya - Dabbobin Dabbobi

Wadatacce

Ciwon ƙwayar mast a cikin kuliyoyi na iya gabatarwa ta hanyoyi biyu: cutaneous da visceral. Ciwon ƙwayar mast ɗin cutaneous shine mafi yawa kuma shine nau'in na biyu m ciwon daji ya fi yawa a cikin kuliyoyi. Ciwon ƙwayar mastis na ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta.

Ana yin ganewar asali ta hanyar cytology ko biopsy a cikin cututtukan ƙwayar ƙwayar ƙwayar mast na fata, da kuma ta hanyar cytology, gwajin jini da ganewar hoto a cikin ƙwayar ƙwayar ƙwayar mast na visceral. Magani ne ta hanyar tiyata a lokuta biyu, ko da yake a wasu iri visceral mast cell marurai da shi ba a nuna, ta amfani da jiyyar cutar sankara da kuma taimaka kwayoyi don inganta ingancin rayuwa da Cats da mast cell siffofin maruran. Ci gaba da karanta wannan labarin PeritoAnimal don ƙarin koyo game da shi mast cell tumor, alamunta, magani da hasashe.


Mene ne mast cell tumo a cats

Mastocytoma yana daya daga cikin nau'in ciwace -ciwacen da zai iya shafar kuliyoyin da suka kunshi ƙari mast cell multiplication. Kwayoyin mast sune sel waɗanda suka samo asali a cikin kasusuwan kasusuwa daga ƙaddarar hematopoietic kuma ana iya samun su a cikin fata, nama mai haɗawa, sashin gastrointestinal, da fili na numfashi.

Shin sel masu kariya layin farko akan wakilan masu kamuwa da cuta da garkuwoyinsu sun ƙunshi abubuwan da ke shiga tsakani na rashin lafiyan da halayen kumburi, kamar histamine, TNF-α, IL-6, proteases, da sauransu.

Lokacin da kumburin waɗannan sel ya faru, abubuwan da ke cikin ƙwanƙolin su ana sakin su ta hanyar wuce gona da iri, suna haddasawa tasirin gida ko tsarin wanda zai iya haifar da alamomi daban -daban na asibiti dangane da wurin da suke.


Ire -iren kumburin mast cell

A cikin kuliyoyi, ƙwayoyin mast cell na iya zama na fata, lokacin da suke kan fata; ko visceral, lokacin da yake cikin viscera na ciki.

Ciwon ƙwayar mast cell

Yana da ƙwayar cuta ta biyu mafi yawa a cikin kuliyoyi da na huɗu a cikin duk kumburin ƙurji. Kwayoyin Siamese suna da alama suna iya fama da cututtukan ƙwayar ƙwayar mast. Suna wanzu hanyoyi biyu na ciwan kumburin ƙwayar mast ɗin cutaneous gwargwadon halayen tarihin su:

  • mastocytosis: yana faruwa galibi a cikin kuliyoyi sama da shekaru 9 kuma yana rarrabuwa cikin madaidaicin sifa (mafi yawan lokuta kuma mara kyau, har zuwa 90% na lokuta) da nau'in watsawa (mafi muni, kutsawa da haifar da metastasis).
  • Tarihi: Yana faruwa tsakanin shekaru 2 zuwa 10.

visceral mast cell tumor

Ana iya samun waɗannan ƙwayar mast cell gabobin parenchymal kamar:


  • Spleen (mafi yawan lokuta).
  • Ƙananan hanji.
  • Magungunan lymph na Mediastinal.
  • Mesenteric lymph nodes.

Musamman yana shafar tsofaffin kuliyoyi tsakanin 9 da 13 shekaru allahntaka.

Alamomin mast cell ciwon daji a cikin kuliyoyi

dangane da nau'in kumburin mast cell tumor, alamu na iya bambanta, kamar yadda za mu gani a ƙasa.

Alamun cutukan mast cell tumor a cikin kuliyoyi

Cututtukan mast cell cutters a cats na iya zama talakawa daya ko mahara (20% na lokuta). Ana iya samun su a kai, wuya, kirji ko gabobi, da sauransu.

Kunshi nodules waxanda yawanci:

  • An ayyana.
  • 0.5-3 cm a diamita.
  • Ba launin fata ko ruwan hoda ba.

Wasu alamun asibiti wanda zai iya bayyana a cikin yankin tumor shine:

  • Erythema.
  • Ciwon mara na sama.
  • Itching na lokaci -lokaci.
  • Raunin kai.
  • Kumburi.
  • Subcutaneous edema.
  • Anaphylactic dauki.

Tarihin mast cell nodules yawanci bace kwatsam.

Alamomin ciwon kumburin mast cell cell a cikin kuliyoyi

Cats tare da ƙwayar ƙwayar mast na visceral suna nuna alamun cuta tsarin, kamar:

  • Amai.
  • Damuwa.
  • Ciwon mara.
  • Rage nauyi.
  • Zawo.
  • Hyporexia.
  • Wahalar numfashi idan akwai kumburin ciki.
  • Splenomegaly (girman saifa).
  • Ascites.
  • Hepatomegaly (hanta mai girma).
  • Karancin jini (14-70%).
  • Mastocytosis (31-100%).

Lokacin da cat ya gabatar canje -canje a cikin jini, kamar faɗaɗawa, nodules, ko haɗaɗɗun gabobin jikin mutum, abu na farko da za a yi tunani shi ne ƙwayar ƙwayar mast.

Binciken ƙwayar ƙwayar mast cell

Binciken zai dogara ne akan nau'in ƙwayar ƙwayar mast ɗin da likitan dabbobi ke zargin cewa dabbar na iya fama da ita.

Binciken ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta a cikin kuliyoyi

Ana tuhumar kumburin ƙwayar mast ɗin ƙwayar cuta a cikin kuliyoyi lokacin da nodule tare da halayen da aka bayyana a sama ya bayyana, wanda wani cytology ko biopsy.

Ciwon ƙwayar mast ɗin Histicitic shine mafi wahalar ganewa ta hanyar ilimin cytology saboda halayen salularsa, ƙima mai yawa da kasancewar ƙwayoyin lymphoid.

Ya kamata a yi la'akari da cewa, a cikin feline eosinophilic granuloma, ƙwayoyin mast na iya bayyana, wanda na iya haifar da ba daidai ba ganewar asali.

Ganewar asali da visceral mast cell marurai a Cats

O bambancin ganewar asali na feline visceral mast cell marurai, musamman cewa daga cikin baƙin ciki, ya hada da wadannan matakai:

  • Maza.
  • Sakin kayan haɗi.
  • Hemangiosarcoma.
  • Nodular hyperplasia.
  • Lymphoma.
  • Myeloproliferative cuta.

Ƙididdigar jini, biochemistry da gwaje -gwajen hoto suna da mahimmanci don tantance ƙwayar ƙwayar ƙwayar mast na visceral:

  • Gwajin jini: akan gwajin jini, ana iya zargin mastocytosis da anemia. Musamman kasancewar mastocytosis, wanda shine halayyar wannan tsari a cikin kuliyoyi.
  • Duban dan tayi: duban dan tayi zai iya gano splenomegaly ko taro na hanji kuma ya nemi metastases a cikin ƙwayoyin lymph na mesenteric ko wasu gabobin kamar hanta. Hakanan yana ba ku damar ganin canje -canje a cikin parenchyma ko nodules.
  • x-ray na kirji: CXR yana ba mu damar lura da yanayin huhu, neman metastases, zubar jini ko canje -canje a cikin cranial mediastinum.
  • Cytology: Kyakkyawar allurar cytology a cikin hanta ko hanji na iya bambanta ƙwayar ƙwayar mast daga wasu hanyoyin da aka bayyana a cikin ganewar bambancin. Idan an yi shi a cikin ruwa mai ɗaci ko ruwa, ana iya ganin mast sel da eosinophils.

Jiyya na mast cell marurai a Cats

Maganin da za a bi zai kuma gabatar da wasu bambance -bambancen gwargwadon nau'in ƙwayar ƙwayar mast ɗin da za a bi.

Jiyya na ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta a cikin kuliyoyi

Ana yin maganin ƙwayar ƙwayar mast cell cutaneous tare da tiyata tiyata, har ma a lokuta na siffofin histiocytic, waɗanda ke saurin koma baya kwatsam.

Yin tiyata yana da warkewa kuma dole ne a yi shi ta hanyar jujjuyawar gida, a cikin lamuran ƙwayoyin mast, kuma tare da ƙarin munanan rikice -rikice a cikin lokutan watsawa. Gaba ɗaya, da kau na gida tare da gefe tsakanin 0.5 da 1 cm ana ba da shawarar ga kowane ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta da aka gano ta hanyar binciken cytology ko biopsy.

Maimaitawa a cikin ƙwayar ƙwayar ƙwayar mast ɗin ƙwayar cuta ba safai ake samun ta ba, har ma da cirewar da ba a cika ba.

Jiyya na visceral mast cell marurai a Cats

DA cire tiyata na visceral mast cell ƙari da aka yi a Cats da wani hanji taro ko baƙin ciki ba tare da metastases sauran wurare. Kafin cirewa, da amfani da antihistamines kamar cimetidine ko chlorpheramine ana ba da shawarar don rage haɗarin lalacewar ƙwayar mast, wanda zai haifar da matsaloli kamar ulcers na ciki, ƙin abubuwan da ba su dace ba da hypotension.

Matsakaicin lokacin rayuwa bayan splenectomy yana tsakanin 12 da 19 watanni, amma dalilai marasa kyau na hasashe sun haɗa da kuliyoyi tare da anorexia, asarar nauyi mai nauyi, anemia, mastocythemia, da metastasis.

Bayan tiyata, galibi ana gudanar da shi Chemotherapy na gaba tare da prednisolone, vinblastine ko lomustine.

A cikin yanayin metastasis ko shigar da tsarin, ana iya amfani da prednisolone na baka a allurai na 4-8 MG/kg kowane awanni 24-48. Idan ana buƙatar ƙarin wakilin chemotherapeutic, ana iya amfani da chlorambucil da baki a kashi na 20 mg/m2 kowane mako biyu.

Don inganta alamun wasu kuliyoyi, magungunan antihistamine don rage yawan acidity na ciki, tashin zuciya da haɗarin ulcer na ciki, antiemetics, abubuwan motsa jiki ko analgesics.

Yanzu da kuka san komai game da kumburin mast cell, muna ba da shawarar bidiyo mai zuwa game da cututtukan da suka fi yawa a cikin kuliyoyi:

Wannan labarin don dalilai ne kawai na bayanai, a PeritoAnimal.com.br ba za mu iya rubuta magungunan dabbobi ko yin kowane irin ganewar asali ba. Muna ba da shawarar cewa ku kai dabbar ku ga likitan dabbobi idan tana da kowane irin yanayi ko rashin jin daɗi.

Idan kuna son karanta ƙarin labarai makamantansu Mast cell ciwon sukari a cikin cats - Alamun, magani da tsinkaya, muna ba da shawarar ku shigar da mu Sauran sassan matsalolin lafiya.